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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANAPC4 All Species: 30.3
Human Site: S105 Identified Species: 60.61
UniProt: Q9UJX5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJX5 NP_037499.2 808 92116 S105 P E S L H S F S V E A P V S C
Chimpanzee Pan troglodytes XP_001165326 808 92071 S105 P E S L H S F S V E A P V S C
Rhesus Macaque Macaca mulatta XP_001082716 809 92216 S105 P E S L H S F S V E A P V S C
Dog Lupus familis XP_536270 808 91824 S105 P E S L H S F S V E A P V S C
Cat Felis silvestris
Mouse Mus musculus Q91W96 807 91689 S105 P E S L H S F S V E A P V S C
Rat Rattus norvegicus NP_001100690 807 91758 S105 P E S L H S F S V E A P V S C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513880 760 86226 H95 V E K P E S L H S F S V D T T
Chicken Gallus gallus XP_001231777 799 90763 S98 P E S L H S F S V N L S I T Y
Frog Xenopus laevis NP_001084578 789 89642 S98 P E S L H S F S L E T P I S C
Zebra Danio Brachydanio rerio NP_001008589 797 89831 P98 A E I L H L F P V E Y P A S C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393301 694 78535 L29 W S P K M D L L A I A N I K G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203585 714 79653 P49 R L T W Q R Q P I W T L S P P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.1 97.5 N.A. 93.4 93.6 N.A. 73.8 74.7 70.7 62.2 N.A. N.A. 29.4 N.A. 38.1
Protein Similarity: 100 100 99.5 98.5 N.A. 96.5 96.5 N.A. 83.2 85.1 82.5 77.2 N.A. N.A. 50.6 N.A. 55.5
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 13.3 60 80 60 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 26.6 73.3 93.3 60 N.A. N.A. 13.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 0 0 0 9 0 59 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67 % C
% Asp: 0 0 0 0 0 9 0 0 0 0 0 0 9 0 0 % D
% Glu: 0 84 0 0 9 0 0 0 0 67 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 75 0 0 9 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % G
% His: 0 0 0 0 75 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 0 0 0 0 0 9 9 0 0 25 0 0 % I
% Lys: 0 0 9 9 0 0 0 0 0 0 0 0 0 9 0 % K
% Leu: 0 9 0 75 0 9 17 9 9 0 9 9 0 0 0 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 9 0 9 0 0 0 % N
% Pro: 67 0 9 9 0 0 0 17 0 0 0 67 0 9 9 % P
% Gln: 0 0 0 0 9 0 9 0 0 0 0 0 0 0 0 % Q
% Arg: 9 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 9 67 0 0 75 0 67 9 0 9 9 9 67 0 % S
% Thr: 0 0 9 0 0 0 0 0 0 0 17 0 0 17 9 % T
% Val: 9 0 0 0 0 0 0 0 67 0 0 9 50 0 0 % V
% Trp: 9 0 0 9 0 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _